A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia.
Synonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone
Term information
- PMID:19283350
- PMID:20955109
- LINCS:LSM-5505
- PMID:23859348
- PMID:7981485
- Patent:US4271083
- Patent:DE2519730
- PMID:18710357
- PMID:33254077
- CAS:58186-27-9
- DrugBank:DB09081
- KEGG:D01750
- PMID:15374364
- PMID:2669658
- PMID:33628024
- PMID:11207459
- Chemspider:3558
- PMID:32111141
- PMID:18045357
- PMID:22269948
- Reaxys:2001459
- Drug_Central:1416
- PMID:7988944
- PMID:19283347
- Wikipedia:Idebenone
- PMID:30726629
- PMID:33247801
3_STAR
CAS:58186-27-9
PMID:7981485
PMID:19283347
KEGG:D01750
Chemspider:3558
PMID:33254077
Wikipedia:Idebenone
LINCS:LSM-5505
DrugBank:DB09081
PMID:11207459
Patent:DE2519730
PMID:15374364
PMID:18045357
PMID:20955109
PMID:32111141
PMID:33628024
PMID:7988944
Reaxys:2001459
Patent:US4271083
PMID:2669658
PMID:23859348
PMID:30726629
PMID:22269948
Drug_Central:1416
PMID:33247801
PMID:19283350
PMID:18710357
Raxone
2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone
CV 2619
CV-2619
idebenonum
6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
idebenona
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
idebenone
6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone
InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3