1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Synonyms: CLONAZEPAM 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Term information
- Beilstein:759557
- PMID:12213069
- Drug_Central:703
- DrugBank:DB01068
- PMID:12873507
- Patent:US3116203
- CAS:1622-61-3
- Patent:US3335181
- KEGG:D00280
- Patent:US3121076
- PMID:10633040
- Wikipedia:Clonazepam
3_STAR
PMID:12873507
CAS:1622-61-3
Patent:US3335181
Patent:US3121076
Wikipedia:Clonazepam
Drug_Central:703
Patent:US3116203
DrugBank:DB01068
PMID:12213069
PMID:10633040
Beilstein:759557
KEGG:D00280
5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one
clonazepamum
clonazepam
5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one
InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)