A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
Synonyms: (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid ETODOLAC
Term information
- Wikipedia:Etodolac
- CAS:41340-25-4
- Patent:DE2301525
- LINCS:LSM-1781
- PMID:2970548
- Patent:US3939178
- PMID:2527995
- DrugBank:DB00749
- HMDB:HMDB0014887
- PMID:15369391
- PMID:28166217
- Drug_Central:1103
- KEGG:D00315
3_STAR
PMID:15369391
HMDB:HMDB0014887
LINCS:LSM-1781
PMID:28166217
DrugBank:DB00749
Drug_Central:1103
CAS:41340-25-4
PMID:2527995
Patent:DE2301525
KEGG:D00315
Wikipedia:Etodolac
Patent:US3939178
PMID:2970548
1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
etodolaco
ETODOLIC ACID
(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
(+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
etodolac
etodolacum
InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)