A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Synonyms: [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Term information
- Reaxys:497341
- CAS:53-86-1
- PMID:22931205
- PMID:5952296
- HMDB:HMDB0014473
- KEGG:C01926
- Gmelin:1446006
- Patent:US3161654
- Drug_Central:1440
- PDBeChem:IMN
- Wikipedia:Indometacin
- DrugBank:DB00328
- PMID:28166217
- Patent:BE379378
- KEGG:D00141
- PMID:6039425
- KNApSAcK:C00030512
- Beilstein:497341
- MetaCyc:CPD-10545
- PMID:23992308
- LINCS:LSM-3275
3_STAR
KEGG:D00141
Patent:US3161654
Gmelin:1446006
PMID:6039425
PDBeChem:IMN
KEGG:C01926
HMDB:HMDB0014473
LINCS:LSM-3275
PMID:28166217
PMID:5952296
DrugBank:DB00328
Reaxys:497341
Beilstein:497341
Drug_Central:1440
PMID:22931205
Patent:BE379378
CAS:53-86-1
MetaCyc:CPD-10545
Wikipedia:Indometacin
PMID:23992308
KNApSAcK:C00030512
1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
indometacina
indometacine
Indocin
indometacin
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Aconip
Indomethacin
indometacinum
InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)