An aromatic amide obtained by formal condensation of the carboxy group of 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid with the secondary amino group of 5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole. An orexin receptor antagonist used for the management of insomnia.
Synonyms: [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone
Term information
- Wikipedia:Suvorexant
- CAS:1030377-33-3
- KEGG:D10082
- PMID:25231363
- PMID:24550770
- PMID:24680372
- Reaxys:18339082
- PMID:25197807
- PMID:24368893
- PMID:25167596
- PMID:25291725
- PMID:25299902
- PMID:25227290
- PMID:23692283
- PMID:24757363
- PMID:23372274
- Drug_Central:4881
- PMID:24488306
3_STAR
PMID:24757363
PMID:24550770
PMID:24488306
Wikipedia:Suvorexant
PMID:24680372
PMID:25197807
KEGG:D10082
PMID:23692283
CAS:1030377-33-3
PMID:25167596
PMID:24368893
PMID:25291725
Drug_Central:4881
PMID:25227290
Reaxys:18339082
PMID:23372274
PMID:25231363
PMID:25299902
InChI=1S/C23H23ClN6O2/c1-15-3-5-20(30-25-8-9-26-30)18(13-15)22(31)29-12-11-28(10-7-16(29)2)23-27-19-14-17(24)4-6-21(19)32-23/h3-6,8-9,13-14,16H,7,10-12H2,1-2H3/t16-/m1/s1