Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO]
Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].
Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO]
Synonyms: epencephalon-1
Term information
- UMLS:C1268981
- ZFA:0000100
- GAID:595
- EHDAA2:0000232
- CALOHA:TS-0125
- AAO:0010485
- null:http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643
- VHOG:0000024
- MESH:D002531
- UMLS:C0007765
- null:http://linkedlifedata.com/resource/umls/id/C0007765
- BAMS:CB
- null:http://www.snomedbrowser.com/Codes/Details/180924008
- null:http://en.wikipedia.org/wiki/Cerebellum
- MAT:0000110
- BAMS:Cb
- NCIT:C12445
- XAO:0003098
- HBA:4696
- BTO:0000232
- MA:0000198
- EMAPA:17787
- BIRNLEX:1489
- MBA:512
- TAO:0000100
- MIAA:0000110
- EV:0100293
- DHBA:10656
- BM:CB
- null:http://linkedlifedata.com/resource/umls/id/C1268981
- FMA:67944
- OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA
- EFO:0000327
uberon_slim, efo_slim, pheno_slim, vertebrate_core
UMLS:C0007765
FMA:67944
UMLS:C1268981
XAO:0003098
http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643
http://en.wikipedia.org/wiki/Cerebellum
AAO:0010485
EMAPA:17787
BTO:0000232
HBA:4696
TAO:0000100
CALOHA:TS-0125
http://linkedlifedata.com/resource/umls/id/C0007765
BAMS:Cb
GAID:595
MA:0000198
MAT:0000110
ZFA:0000100
MBA:512
EFO:0000327
DHBA:10656
http://linkedlifedata.com/resource/umls/id/C1268981
MESH:D002531
OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA
BM:CB
http://www.snomedbrowser.com/Codes/Details/180924008
MIAA:0000110
EHDAA2:0000232
EV:0100293
VHOG:0000024
BAMS:CB
NCIT:C12445
BIRNLEX:1489
almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem
However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]
The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full]