acetophenazine
|
CHEBI_2401 |
[A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2.] |
glycerophospholipid
|
CHEBI_37739 |
[Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone.] |
DYRK1A
|
OGG_3000001859 |
|
Alzheimer disease 19
|
MONDO_0014316 |
[Any Alzheimer disease in which the cause of the disease is a mutation in the PLD3 gene.] |
chemical synaptic transmission
|
GO_0007268 |
[The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.] |
BACE1
|
OGG_3000023621 |
|
DVL1
|
OGG_3000001855 |
|
basal ganglion
|
UBERON_0002420 |
[An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified].] |
hippocampal formation
|
UBERON_0002421 |
[Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment].] |
MAPK cascade
|
GO_0000165 |
[An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.] |
FDG-Positron Emission Tomography
|
NCIT_C103400 |
[An imaging technique that utilizes positron emission tomography to produce a three-dimensional image of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on the biologically active molecule (fludeoxyglucose) FDG. FDG is an analogue of glucose which when imaged will give tissue metabolic activity, in terms of regional glucose uptake.] |
Functional Magnetic Resonance Imaging
|
NCIT_C17958 |
[The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function.] |
fragmented DNA
|
FYPO_0000160 |
[A cell phenotype in which DNA is broken into small fragments.] |
striatum
|
UBERON_0002435 |
[A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO].] |
Pathogen-Associated Molecular Pattern Molecules
|
OMIT_0001440 |
|
organismal assay
|
ERO_0001285 |
[An assay that generates data about the physical characteristics, physological functions, or behavior of organisms or viruses.] |
lumiracoxib
|
CHEBI_73044 |
[An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity.] |
physiological assay
|
ERO_0001292 |
[An organismal assay designed to capture information pertaining to the the organic processes and phenomena of an organism or any of its parts or of a particular bodily process.] |
Genotype
|
NCIT_C16631 |
[The genetic constitution of an organism or cell, as distinct from its expressed features or phenotype.] |
Retrospective Cohort Study
|
NCIT_C93228 |
|