Maprotiline
|
CHEBI_6690 |
|
PSEN1
|
OGG_3000005663 |
|
IGF1R
|
OGG_3000003480 |
|
N-acetyl-D-glucosamine
|
CHEBI_506227 |
[The D isomer of N-acetylglucosamine.] |
TM_BIN_isTreatmentFor
|
ADO_0000012 |
|
phosphatidic acid
|
CHEBI_16337 |
[A derivative of glycerol in which one hydroxy group, commonly but not necessarily primary, is esterified with phosphoric acid and the other two are esterified with fatty acids.] |
TM_BIN_isSignAndSymptomFor
|
ADO_0000011 |
|
TM_BIN_VariantisGeneticRiskFactorFor
|
ADO_0000010 |
|
PORCN
|
OGG_3000064840 |
|
mild cognitive impairment due to Alzheimer's disease
|
ADO_0000049 |
[A stage of Alzheimer's disease where symptoms appear such as concern regarding a change in cognition (raised either by the patient himself/herself or by an informant who knows the patient well), impairment in one or more cognitive domains, preservation of independence in functional abilities and other non-demented symptoms.] |
preclinical stage of Alzheimer's disease
|
ADO_0000048 |
[A disease stage of Alzheimer's disease that begins long before any symptoms become apparent. The symptoms go unnoticed by the patients and people around them and this stage can last for years, possibly even decades.] |
serotonin
|
CHEBI_28790 |
[A primary amino compound that is the 5-hydroxy derivative of tryptamine.] |
late endosome
|
GO_0005770 |
[A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.] |
neuronal stem cell
|
CL_0000047 |
[Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors.] |
Guanine Nucleotide Exchange Factors
|
OMIT_0020519 |
|
autophagosome
|
GO_0005776 |
[A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.] |
rivastigmine
|
CHEBI_8874 |
[A carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor.] |
SLC2A4
|
OGG_3000006517 |
|
risperidone
|
CHEBI_8871 |
[A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.] |
Thiazolidinedione Antidiabetic Agent
|
NCIT_C98241 |
[Any antidiabetic agent with the glitazone (thiazolidinedione) base structure with antihyperglycemic activity. Glitazone antidiabetic agents selectively bind to and stimulate the nuclear receptor peroxisome proliferator-activated receptor (PPAR) gamma. This results in the selective transcription of a number of insulin-sensitive genes involved in glucose metabolism. This eventually enhances insulin sensitivity, reduces insulin resistance and decreases hepatic gluconeogenesis. PPARs function as transcription factors that regulate expressions of genes involved in cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), as well as tumorigenesis; PPARgamma is expressed at high levels in adipose tissue.] |