Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed [A32451]. Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120]. Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more. At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.

Synonyms: Vitamin E acetate, D- D-alpha tocopheryl acetate D-alpha-Tocopherol acetate RRR-alpha-tocopheryl acetate alpha-tocopheryl acetate, D- DBSALT001457 D-alpha-Tocopheryl acetate (+)-alfa-tocopherol acetate D-alpha tocoferil acetate

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Term information

database cross reference
  • CAS:58-95-7
  • Drugs Product Database (DPD):2295
  • KEGG Drug:D01735
  • Drugs Product Database (DPD):4929
  • KEGG Compound:C13202
  • ChemSpider:77987
  • ChEBI:32321
  • Wikipedia:Tocopheryl_acetate
  • ChEMBL:CHEMBL1047
exactMatch

drugbank:DBSALT001457

hasDbXref

Drugs Product Database (DPD):2295

Drugs Product Database (DPD):4929

ChemSpider:77987

KEGG Compound:C13202

ChEBI:32321

ChEMBL:CHEMBL1047

CAS:58-95-7

KEGG Drug:D01735

Wikipedia:Tocopheryl_acetate

inScheme

https://identifiers.org/drugbank

label

D-alpha-Tocopherol acetate

Term relations

Subclass of: