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Choline alfoscerate
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DB04660 |
[A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]] |
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Plinabulin
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DB05992 |
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S-(N-hydroxy-N-iodophenylcarbamoyl)glutathione
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DB03330 |
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cis-tetracosenoyl sulfatide
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DB04661 |
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Obeticholic acid
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DB05990 |
[Obeticholic acid is a farnesoid-X receptor (FXR) agonist and is used to treat a number of liver diseases. [A18696] Obeticholic acid has been granted accelerated approval to treat primary biliary cholangitis in combination with ursodeoxycholic acid. [A18696] Approval is limited to monotherapy in patient's who are intolerant to ursodeoxycholic acid, or in combination with ursodeoxycholic acid in adults who have not responded adequately to ursodeoxyholic acid alone. [A18696]
Obeticholic acid given orally, binds to the farnesoid X receptor (FXR), a receptor found in the nucleus of cells in the liver and intestine. FXR is a key regulator of bile acid metabolic pathways. Obeticholic acid increases bile flow from the liver and suppresses bile acid production in the liver, thus reducing the exposure of the liver to toxic levels of bile acids.] |
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VM4-037
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DB15319 |
[VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).] |
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Neodymium
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DB15318 |
[Neodymium is under investigation in clinical trial NCT03525522 (Nd:Yttrium Aluminum Garnet Laser Treatment for Lichen Sclerosus).] |
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Coblopasvir
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DB15315 |
[Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).] |
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Modimelanotide
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DB15314 |
[Modimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Surgery).] |
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Posiphen
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DB15317 |
[Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).] |
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Florasulam
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DB15316 |
[Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station).] |
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Davanat
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DB15311 |
[Davanat is under investigation in clinical trial NCT00054977 (Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors).] |
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Vactosertib
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DB15310 |
[Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).] |
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DAS-181
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DB15313 |
[DAS-181 is under investigation in clinical trial NCT00527865 (Single Dose Escalating Study of DAS181 in Adults).] |
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Orilanolimab
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DB15312 |
[Orilanolimab is under investigation in clinical trial NCT03075878 (A Safety Study of SYNT001 in Subjects With Chronic, Stable Warm Autoimmune Hemolytic Anemia (WAIHA)).] |
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L-756423
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DB02009 |
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1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine
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DB02008 |
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3-Iodo-Benzyl Alcohol
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DB03339 |
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CHROMOPHORE (GLU-TYR-GLY)
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DB04668 |
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2-Oxo-3-Pentenoic Acid
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DB02005 |
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