The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. [ http://www.ncbi.nlm.nih.gov/pubmed/9412464 GOC:autophagy ]
Synonyms: autophagosome biosynthesis autophagosome formation autophagic vacuole assembly
Term information
Term relations
- organelle assembly
- autophagosome organization
- has part some Atg12 conjugating enzyme activity
- has part some Atg12 activating enzyme activity
- has part some Atg1/ULK1 kinase complex assembly
- has part some protein-phosphatidylethanolamide deconjugating activity
- has part some Atg12 ligase activity