Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. [ https://www.worldcat.org/search?q=bn%3A0781735149 GOC:add http://purl.obolibrary.org/obo/go/references/0000022 http://www.ncbi.nlm.nih.gov/pubmed/15199967 http://www.ncbi.nlm.nih.gov/pubmed/16177805 GOC:mtg_sensu ]