cytoplasmic pattern recognition receptor signaling pathway
Go to external page http://purl.obolibrary.org/obo/GO_0002753
The series of molecular signals initiated by the binding of a ligand from another organism to a cytoplasmic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. [ http://www.ncbi.nlm.nih.gov/pubmed/15199967 http://www.ncbi.nlm.nih.gov/pubmed/18272355 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/21187438 http://www.ncbi.nlm.nih.gov/pubmed/19531363 http://www.ncbi.nlm.nih.gov/pubmed/17328678 GOC:ar https://www.worldcat.org/search?q=bn%3A0781735149 ]
Synonyms: cytosolic pattern recognition receptor signaling pathway cytoplasmic pathogen receptor signaling pathway cytoplasmic PRR signaling pathway cytosolic PAMP receptor signaling pathway cytoplasmic pattern recognition receptor signalling pathway
Term information
This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has been activated. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.
https://github.com/geneontology/go-ontology/issues/18588
https://github.com/geneontology/go-ontology/issues/17080