Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity. [ https://www.worldcat.org/search?q=bn%3A0198547684 ]
Synonyms: protein phosphatase activity phosphoprotein phosphohydrolase activity
Term information
- Reactome:R-HSA-170153 (Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases)
- Reactome:R-HSA-178178 (PP1 dephosphorylates TGFBR1)
- Reactome:R-HSA-174124 (Dephosphorylation of phospho-Cdh1)
- Reactome:R-HSA-69199 (Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A)
- Reactome:R-HSA-2529015 (Dephosphorylation of CK2-modified condensin I)
- Reactome:R-HSA-112383 (Hypophosphorylation of RNA Pol II CTD by FCP1P protein)
- Reactome:R-HSA-170158 (Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes)
- Reactome:R-HSA-1363274 (Dephosphorylation of p107 (RBL1) by PP2A)
- Reactome:R-HSA-113503 (PP2A mediated localization of RB1 protein in chromatin)
- Reactome:R-HSA-9636684 (NdkA dephosphorylates RAB5A:GTP,RAB7A:GTP)
- Reactome:R-HSA-167072 (Hypophosphorylation of RNA Pol II CTD by FCP1P protein)
- Reactome:R-HSA-174110 (Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2)
- Reactome:R-HSA-1363276 (Dephosphorylation of p130 (RBL2) by PP2A)
- Reactome:R-HSA-170161 (Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B)
protein phosphatase-2A activity
protein phosphatase-2C activity
protein phosphatase-1 activity
protein phosphatase-2B activity