Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide. [ http://www.ncbi.nlm.nih.gov/pubmed/15064408 GOC:vw https://enzyme.expasy.org/EC/1.15.1.1 ]
Synonyms: superoxide:superoxide oxidoreductase activity
Term information
- Reactome:R-HSA-1222469 (SodC reduces superoxide to H2O2)
- RHEA:20696
- Reactome:R-HSA-3299680 (SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix))
- Reactome:R-HSA-3299691 (SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol))
- MetaCyc:SUPEROX-DISMUT-RXN
- Reactome:R-HSA-3777112 (SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space))
- EC:1.15.1.1
- Reactome:R-HSA-1222462 (SodB reduces superoxide to H2O2)
- Reactome:R-HSA-3299682 (SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular))
nickel superoxide dismutase activity
Cu-Zn superoxide dismutase activity
copper, zinc superoxide dismutase activity
Mn, Fe superoxide dismutase
manganese superoxide dismutase activity
ferrisuperoxide dismutase activity
iron superoxide dismutase activity
hemocuprein
nickel superoxide oxidoreductase
Fe-SOD
SOD
erythrocuprein
superoxide dismutase II
hepatocuprein
manganese superoxide oxidoreductase
SODS
zinc superoxide oxidoreductase
iron superoxide oxidoreductase
Mn-SOD
Cu,Zn-SOD
superoxide dismutase I
SODF
SOD-3
SOD-4
cuprein
SOD-1
SOD-2
cytocuprein