long-chain fatty acid transmembrane transporter activity
Go to external page http://purl.obolibrary.org/obo/GO_0005324
Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [ https://www.worldcat.org/search?q=bn%3A0198506732 ]
Term information
- Reactome:R-HSA-382575 (ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix)
- Reactome:R-HSA-434381 (CD36 (FAT) translocates palmitate from the extracellular region to the cytosol)
- Reactome:R-HSA-2046093 (Translocation of tetracosapentaenoyl-CoA to peroxisomes)
- Reactome:R-HSA-5684043 (Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix)
- RHEA:39283
- Reactome:R-HSA-2046087 (Translocation of tetracosahexaenoyl-CoA to peroxisomes)
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
https://github.com/geneontology/go-ontology/issues/26996
https://github.com/geneontology/go-ontology/issues/26445
https://github.com/geneontology/go-ontology/issues/14793