phospholipase C-activating opsin-mediated signaling pathway
Go to external page http://purl.obolibrary.org/obo/GO_0030265
A phospholipase C-activating receptor G protein-coupled receptor signaling pathway that starts with an opsin being activated by a photon, and transmitting the signal through the Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). The second messengers, including cGMP, activate channels that result in transmission of the light signal through the synapses. Typical examples are rhabdomeric photoreceptors in the eyes of protostomes. [ http://www.ncbi.nlm.nih.gov/pubmed/8823931 http://www.ncbi.nlm.nih.gov/pubmed/19720651 http://www.ncbi.nlm.nih.gov/pubmed/22498302 ]
Term information
phospholipase C-activating rhodopsin mediated signaling pathway
rhodopsin mediated G protein signalling, coupled to IP3 second messenger
phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway
rhodopsin mediated G-protein signaling, coupled to IP3 second messenger
rhodopsin mediated G protein signaling, coupled to IP3 second messenger
PLC-activating rhodopsin mediated signaling pathway
rhodopsin mediated G-protein signalling, coupled to IP3 second messenger