eukaryotic 48S preinitiation complex

Go to external page http://purl.obolibrary.org/obo/GO_0033290


The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC. [ GOC:hjd http://www.ncbi.nlm.nih.gov/pubmed/24499181 http://www.ncbi.nlm.nih.gov/pubmed/16510876 http://www.ncbi.nlm.nih.gov/pubmed/29735639 http://www.ncbi.nlm.nih.gov/pubmed/24319994 ]

Synonyms: eukaryotic 48S pre-initiation complex

This is just here as a test because I lose it

Term information

has alternative id

GO:0016283

has obo namespace

cellular_component

has related synonym

eukaryotic 48S initiation complex

id

GO:0033290

term tracker item

https://github.com/geneontology/go-ontology/issues/25067