A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide). [ http://www.ncbi.nlm.nih.gov/pubmed/2651866 http://www.ebi.ac.uk/interpro/entry/IPR008221 ]
Term information
Eukaryotic microorganisms, plants, and probably Gram-positive bacteria, possess a homopolymeric urease. In contrast, urease complexes from gram-negative bacteria studied thus far clearly possess three distinct subunits (alpha, beta and gamma). Tightly bound nickel is present in all urease complexes.