A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. [ http://www.ncbi.nlm.nih.gov/pubmed/15215856 GOC:PARL http://www.ncbi.nlm.nih.gov/pubmed/16186510 GOC:bf ]
Synonyms: Derlin-1 retrotranslocon Derlin-1 retro-translocation complex Derlin-1 protein dislocation complex Derlin-1 complex ERAD protein dislocation complex
Term information
The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.