killing by virus of host cell by post-segregational killing
Go to external page http://purl.obolibrary.org/obo/GO_0044696
The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes. [ http://en.wikipedia.org/wiki/Toxin-antitoxin_system GOC:jl http://www.ncbi.nlm.nih.gov/pubmed/11222604 GOC:bf ]
Synonyms: killing by virus of host cell by PSK killing by virus of host cell by toxin-antitoxin system