A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6. [ http://www.ncbi.nlm.nih.gov/pubmed/30415835 http://www.ncbi.nlm.nih.gov/pubmed/32459176 http://www.ncbi.nlm.nih.gov/pubmed/29242231 ]
Term information
Note that this complex used to be thought to be involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane, but newer findings show that this was incorrect.
https://github.com/geneontology/go-ontology/issues/13657
https://github.com/geneontology/go-ontology/issues/20234