mitochondrial outer membrane permeabilization

mitochondrial outer membrane permeabilization

http://purl.obolibrary.org/obo/GO_0097345

The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. [ GOC:BHF GOC:pg GOC:mtg_apoptosis http://www.ncbi.nlm.nih.gov/pubmed/21041309 ]

Synonyms: MOMP mitochondrion outer membrane permeabilization

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This is just here as a test because I lose it

Term information

comment

BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).

created by

creation date

2012-06-19T04:06:54Z

has broad synonym

mitochondrial outer membrane permeabilization during apoptotic cell death

has obo namespace

biological_process

GO:0097345

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regulates

regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

positively regulates

positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negatively regulates

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway