Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. [ http://www.ncbi.nlm.nih.gov/pubmed/26517899 ]
Synonyms: ABC-type uptake permease activity ABC-type efflux permease activity ATP binding cassette transporter ABC-type efflux porter activity ABC-type transmembrane transporter activity ATP-binding cassette transporter ABC transporter ATP-binding cassette (ABC) transporter activity
Term information
- Reactome:R-HSA-5362459 (VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol)
- Reactome:R-HSA-9661405 (ABCC1 transports BIL from cytosol to extracellular region (blood))
- Reactome:R-HSA-429157 (ABCC4 accumulation of dense granule contents)
- Reactome:R-HSA-9750656 (ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells)
- TC:3.A.1
- Reactome:R-HSA-5387389 (Hh processing variants are translocated to the cytosol in a VCP-dependent manner)
- Wikipedia:ATP-binding_cassette_transporter
- Reactome:R-HSA-266070 (LTC4 is exported from the cytosol by ABCC1)
https://github.com/geneontology/go-ontology/issues/21273
https://github.com/geneontology/go-ontology/issues/20529