facultative heterochromatin formation

Go to external page http://purl.obolibrary.org/obo/GO_0140718


The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27. [ http://www.ncbi.nlm.nih.gov/pubmed/17936700 ]

Synonyms: fHC assembly facultative heterochromatin assembly

This is just here as a test because I lose it

Term information

comment

Note that facultative heterochromatin can be reprogrammed, as opposed to constitutive heterochromatin which usually cannot be reprogrammed to a transcriptionally-competent state. Note also that facultative heterochromatin formation does not usually involve DNA methylation, while constitutive heterochromatin formation does.

creation date

2021-10-29T13:40:47Z

has obo namespace

biological_process

id

GO:0140718

term tracker item

https://github.com/geneontology/go-ontology/issues/23553

https://github.com/geneontology/go-ontology/issues/22325

Term relations