epigenetic programming in the zygotic pronuclei
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GO_0044725 |
[The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.] |
epigenetic programming of gene expression
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GO_0043045 |
[A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation.] |
epigenetic programing of female pronucleus
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GO_0044726 |
[The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.] |
epigenetic programing of male pronucleus
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GO_0044727 |
[The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division.] |
obsolete DNA methylation or demethylation
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GO_0044728 |
[OBSOLETE. The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.] |
obsolete ubiquitin-like hydrolase activity
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GO_0019790 |
[OBSOLETE. (Was not defined before being made obsolete).] |
hemi-methylated DNA-binding
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GO_0044729 |
[Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.] |
double-stranded DNA binding
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GO_0003690 |
[Binding to double-stranded DNA.] |
FAT10 activating enzyme activity
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GO_0019780 |
[Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.] |
NEDD8 activating enzyme activity
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GO_0019781 |
[Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.] |
ISG15 activating enzyme activity
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GO_0019782 |
[Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.] |
ubiquitin-like protein peptidase activity
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GO_0019783 |
[An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.] |
peptidase activity
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GO_0008233 |
[Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.] |
deNEDDylase activity
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GO_0019784 |
[An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.] |
ISG15-specific peptidase activity
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GO_0019785 |
[A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.] |
cysteine-type peptidase activity
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GO_0008234 |
[Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.] |
negative regulation of imaginal disc-derived wing size
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GO_0044720 |
[Any process that reduces the size of an imaginal disc-derived wing.] |
protein-phosphatidylethanolamide deconjugating activity
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GO_0019786 |
[Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.] |
catalytic activity, acting on a protein
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GO_0140096 |
[Catalytic activity that acts to modify a protein.] |
hydrolase activity
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GO_0016787 |
[Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.] |