retroviral integrase activity
|
GO_0044823 |
[Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.] |
integrase activity
|
GO_0008907 |
[Catalysis of the integration of one DNA segment into another.] |
potassium channel activity
|
GO_0005267 |
[Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel.] |
retroviral 3' processing activity
|
GO_0044824 |
[The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.] |
DNA endonuclease activity
|
GO_0004520 |
[Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.] |
obsolete retroviral strand transfer activity
|
GO_0044825 |
[OBSOLETE. Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.] |
viral genome integration into host DNA
|
GO_0044826 |
[The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.] |
viral process
|
GO_0016032 |
[A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.] |
negative regulation by host of viral genome replication
|
GO_0044828 |
[A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.] |
negative regulation by host of viral process
|
GO_0044793 |
[A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.] |
obsolete bacteriocin susceptibility/resistance
|
GO_0019880 |
[OBSOLETE. (Was not defined before being made obsolete).] |
obsolete streptomycin susceptibility/resistance
|
GO_0019881 |
[OBSOLETE. (Was not defined before being made obsolete).] |
antigen processing and presentation
|
GO_0019882 |
[The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.] |
immune system process
|
GO_0002376 |
[Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.] |
antigen processing and presentation of endogenous antigen
|
GO_0019883 |
[The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.] |
antigen processing and presentation of exogenous antigen
|
GO_0019884 |
[The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.] |
antigen processing and presentation of endogenous peptide antigen via MHC class I
|
GO_0019885 |
[The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.] |
antigen processing and presentation of peptide antigen via MHC class I
|
GO_0002474 |
[The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.] |
antigen processing and presentation of endogenous peptide antigen
|
GO_0002483 |
[The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.] |
antigen processing and presentation of exogenous peptide antigen via MHC class II
|
GO_0019886 |
[The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.] |