A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Synonyms: 0, RNF71 Protein, TRIM19 Protein, Promyelocytic Leukemia Protein
Instance information
comment
2017
identifier
D000071156