A protein interaction domain that is characterized by a bent "beta-sandwich" consisting of two antiparallel beta-sheets. It occurs in eukaryotic proteins, including many TRIPARTITE MOTIF PROTEINS, which function in a variety of cellular processes.

Synonyms: B30.2-SPRY Domain, PRYSPRY Domains, B30.2-SPRY Domains, B30.2 Domain, PRY Domain, PRY Domains, SPRY Domain, PRY-SPRY Domains, B30.2 Domains, B30.2 SPRY Domain, SPRY Domains, PRY-SPRY Domain, PRY SPRY Domain, PRYSPRY Domain