A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.
Synonyms: AlkB Homolog 5, RNA Demethylase, Demethylase ALKBH5, RNA, ALKBH5, RNA Demethylase, RNA Demethylase ALKBH5, Alkylated DNA Repair Protein AlkB Homolog 5, EC 1.14.11.-, Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5, Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 5
Instance information
comment
2017
identifier
D000071502