A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.

Synonyms: 0, Zeb1 Transcription Factor, TCF8 Protein, NIL 2 A Zinc Finger Protein, Zinc Finger E box Binding Homeobox 1, Transcription Factor 8, Transcription Factor, Zeb1, NIL-2-A Zinc Finger Protein, Zinc Finger E-box-Binding Homeobox 1