A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.
Synonyms: GA733 Tumor-Associated Antigen, Epithelial Specific Antigen, Antigen, Epithelial Specific, EpCAM, GA733 Tumor Associated Antigen, Antigen, ESA, Antigen, CD326, GA733, Tumor-Associated Antigen, Tumor-Associated Antigen GA733, GA 733 Tumor-Associated Antigen, Epithelial Cell Adhesion Molecule, GA733 Antigen, 0, Antigen, GA733, CD326 Antigen, GA 733 Tumor Associated Antigen, Tumor Associated Antigen GA733, Ep-CAM, Tumor-Associated Antigen, GA733, ESA Antigen, Tacstd1 Protein, CD326 Protein
Instance information
2017 (1989) ,2017; EPITHELIAL CELL ADHESION MOLECULE was indexed under ANTIGENS, NEOPLASM and CELL ADHESION MOLECULES 1989-2016
D000071858