Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).

Synonyms: AKR1C2 Protein, Dihydrodiol Dehydrogenase Bile Acid Binding Protein, Aldo-Keto Reductase Family 1 Member C2, Dihydrodiol Dehydrogenase-Bile Acid Binding Protein, Dihydrodiol Dehydrogenase 2, Aldo Keto Reductase Family 1 Member C2, EC 1.1.1.357