A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.

Synonyms: A 147627, A147627, Xinlay, A127722.5, A-127722.5, 2-(4-Methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-(((dibutylamino)carbonyl)methyl)pyrrolidine-3-carboxylic acid, 3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-, (2R,3R,4S)-, ABT-627, (11C)ABT-627, A 127722, A-147627, Atrasentan Hydrochloride, ABT 627, Atrasentan, A127722, E4G31X93ZA, 0, A-127722, V6D7VK2215, A 127722.5, ABT627