A major activation of the autophagic pathway, characterized by massive accumulation of AUTOPHAGOSOMES and CELL DEATH.

Synonyms: Deaths, Autophagy-Dependent Cell, Autophagy-Dependent Cell Deaths, Cell Death, Autophagic, Cell Death, Autophagy-Dependent, Deaths, Autophagic Cell, Cell Deaths, Autophagic, Autophagic Cell Deaths, Death, Autophagic Cell, Cell Deaths, Autophagy-Dependent, Autophagic Programmed Cell Death, Autophagic Cell Death, Autophagy Dependent Cell Death, Death, Autophagy-Dependent Cell, Programmed Cell Death, Type II, Autophagy-Dependent Cell Death