Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.

Synonyms: Inhibitory Checkpoint Molecule, Protein, Immune Checkpoint, Immune Checkpoint Protein, Checkpoint Molecule, Inhibitory, Checkpoint Molecule, Immune, Immune Checkpoint Molecule, 0, Checkpoint Protein, Immune, Checkpoint Molecule, Stimulatory, Stimulatory Checkpoint Molecule, Stimulatory Checkpoint Molecules, Immune Checkpoint Molecules, Molecule, Immune Checkpoint, Immune Checkpoint Proteins, Inhibitory Checkpoint Molecules