Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
Synonyms: 0, Anaphylatoxins, Anaphylatoxin
Instance information
comment
90; was see under PEPTIDES 1977-89 ,90(77); was see under PEPTIDES 1977-89
identifier
D000706
Instance relations
Types