Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
Synonyms: SV40 T Antigens, T Proteins, Polyomavirus, Polyomaviruses Large T Proteins, Proteins, SV40 T, Polyomaviruses Small T Proteins, Antigens, Polyomavirus Transforming, Transforming Antigens, Polyomavirus, Polyomavirus Tumor Antigens, Proteins, Polyomavirus T, T Antigens, SV40, Antigens, SV40 T, Tumor Antigens, Polyomavirus, Polyomavirus Middle T Antigens, 0, SV40 T Proteins, Polyomavirus Transforming Antigens, Polyomavirus Large T Antigens, Polyomaviruses Middle T Proteins, Antigens, Polyomavirus Tumor, Polyomavirus T Proteins, T Proteins, SV40, Polyomavirus Small T Antigens, Simian Sarcoma Virus Proteins
Instance information
coordinate with specific polyoma virus /immunol ,88
D000952