Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Synonyms: Brain Disease, Intracranial CNS Disorders, Brain Disorder, Encephalopathies, Encephalon Diseases, Intracranial Central Nervous System Disorders, Central Nervous System Intracranial Disorders, Encephalopathy, Brain Disorders, CNS Disorder, Intracranial, Intracranial CNS Disorder, Brain Diseases, CNS Disorders, Intracranial, Central Nervous System Disorders, Intracranial, Encephalon Disease