A type of developmental disturbance of AMELOGENESIS involving permanent INCISORS and first permanent MOLARS. It is characterized by asymmetrical enamel defects with severe hypomineralization.

An acquired or hereditary condition due to deficiency in the formation of tooth enamel (AMELOGENESIS). It is usually characterized by defective, thin, or malformed DENTAL ENAMEL. Risk factors for enamel hypoplasia include gene mutations, nutritional deficiencies, diseases, and environmental factors.

Synonyms: Molar Incisor Hypomineralization, Enamel Hypoplasia, Hypoplastic Enamel, Dental Enamel Hypoplasia, Hypoplasia, Enamel, Ageneses, Enamel, Enamel Agenesis, Hypoplasia, Dental Enamel, Hypoplasias, Enamel, Enamel Hypoplasia, Dental, Enamel Ageneses, Hypomineralization, Molar Incisor, Enamel Hypoplasias, Agenesis, Enamel, Enamel, Hypoplastic