A degenerating ovarian follicle as a result of atresia (FOLLICULAR ATRESIA). During atresia, the OOCYTE and GRANULOSA CELLS within the basal lamina die and are replaced by fibrous tissue.
The blister-like mature ovarian follicle containing the OVUM surrounded by an accumulation of GRANULOSA CELLS (the cumulus oophorus) and an increasing volume of FOLLICULAR FLUID. The mature Graafian follicle is ready to release the ovum by the process of OVULATION.
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.
Synonyms: Ovarian Follicle, Follicle, Graafian, Atretic Follicle, Follicles, Atretic, Follicle, Atretic, Follicle, Ovarian, Graafian Follicle, Atretic Follicles, Follicles, Ovarian, Follicles, Graafian, Graafian Follicles, Ovarian Follicles
Instance information
99; see GRAAFIAN FOLLICLE 1966-98 ,99 ,/cytol: consider also THECA CELLS; GRANULOSA CELLS; for follicular development use /physiol, not /growth
D006080