A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
Synonyms: LH (Luteinizing Hormone), 9002-67-9, Hormone, Interstitial Cell-Stimulating, Luteozyman, Interstitial Cell Stimulating Hormone, Luteinizing Hormone, 0, Lutropin, Luteoziman, Luteinizing hormone, ICSH (Interstitial Cell Stimulating Hormone), Hormone, Luteinizing, Interstitial Cell-Stimulating Hormone
Instance information
do not confuse entry term LUTROPIN with PLACENTAL LUTEOTROPIN; for alpha subunit, coordinate with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; LUTEINIZING HORMONE, BETA SUBUNIT is also available ,2003 (1968); use ICSH 1963-1967 ,2003; see ICSH 1963-1967
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