Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).

Synonyms: gp120 v fms, fms Oncogene Product gp140, fms Oncogene Product gp120, fms Oncogene Protein gp140, v fms Protein, gp140(v-fms), fms Oncogene Protein gp120, v-fms Protein, gp140 v-fms, gp120 v-fms, 0, Oncogene Protein gp140(v-fms), v-fms, gp120, v-fms, gp140, gp140 v fms, gp120(v-fms)