Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.

Synonyms: beta Lactamase Resistance, beta-Lactam Resistance, beta-Lactamase Resistant, beta-Lactam Resistant, beta Lactamase Resistant, beta-Lactamase Resistance, beta Lactam Resistant, beta Lactam Resistance, Resistant, beta-Lactamase, Resistance, beta-Lactamase