The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)
Synonyms: 0, Breast Cancer 1 Protein, Breast Cancer Type 1 Susceptibility Protein, BRCA1 Gene Product, Ring Finger Protein 53, Breast Cancer 1 Gene Product, BRCA1 Protein
Instance information
97; BCRA1 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1994-96 ,97; was BRCA1 PROTEIN (NM) 1994-96 ,use BRCA1 PROTEIN (NM) to search BRCA1 PROTEIN 1994-96
D019313