Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.
Immunophilins found in the brain.
Synonyms: Immunophilins, Neurophilin, Neurophilins, EC 5.2.1.8, Immunophilin
Instance information
2004; NEUROPHILIN was indexed under LYMPHOKINES 1974-2003; ENDOTHELIAL GROWTH FACTORS 1991-2003 & INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2002 ,don't confuse entry term NEUROPHILINS with NEUROPILINS ,2004(1999); for NEUROPHILIN use VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1997-2003
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