A group of dominantly inherited, predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)

A group of dominantly inherited, predominatly late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)

Synonyms: Spinocerebellar Ataxia 2s, Ataxia 6, Spinocerebellar, Olivopontocerebellar Atrophy II, Spinocerebellar Ataxia 5, Spinocerebellar Atrophy 2s, Spinocerebellar Ataxia 4, Spinocerebellar Ataxia 7, Spinocerebellar Ataxia 6, Olivopontocerebellar Atrophy IV, Spinocerebellar Ataxia with Slow Eye Movements, Ataxia 5s, Spinocerebellar, Cerebelloparenchymal Disorder I, Atrophy I, Olivopontocerebellar, Atrophy IVs, Olivopontocerebellar, Schut-Haymaker Type OPCA, Type 2 Spinocerebellar Ataxia, Spinocerebellar Ataxia 1s, Spinocerebellar Ataxias, Atrophy I, Spinocerebellar, Ataxia 4s, Spinocerebellar, Wadia Swami Syndrome, Atrophy IV, Olivopontocerebellar, Spinocerebellar Atrophy 2, Dominantly Inherited Spinocerebellar Ataxias, Atrophy IIs, Olivopontocerebellar, Atrophy 2, Spinocerebellar, IIs, Olivopontocerebellar Atrophy, Ataxia 1, Spinocerebellar, Type 1 Spinocerebellar Ataxia, Spinocerebellar Ataxia 4s, SCA1, Ataxias, Dominantly-Inherited Spinocerebellar, Spinocerebellar Ataxia, Atrophy 2, Olivopontocerebellar, Autosomal Dominant Cerebellar Ataxia, Type II, Olivopontocerebellar Atrophy III, Atrophy 2s, Olivopontocerebellar, Spinocerebellar Atrophy I, Swami Syndrome, Wadia, Atrophy, Spinocerebellar, OPCA, Menzel Type, Atrophy 2s, Spinocerebellar, Spinocerebellar Degeneration with Slow Eye Movements, Olivopontocerebellar Atrophy IIs, Cerebellar Degeneration with Slow Eye Movements, IIs, Spinocerebellar Atrophy, Cerebelloparenchymal Disorder Is, Ataxia 4, Spinocerebellar, Spinocerebellar Atrophy, Spinocerebellar Atrophy Is, Spinocerebellar Ataxias, Dominantly-Inherited, Type 7 Spinocerebellar Ataxia, Ataxia 7, Spinocerebellar, Ataxia 6s, Spinocerebellar, Dominantly-Inherited Spinocerebellar Ataxias, Spinocerebellar Ataxia, Cuban Type, Spinocerebellar Ataxia 6s, Olivopontocerebellar Atrophy I, Olivopontocerebellar Atrophy IIIs, Ataxia, Dominantly-Inherited Spinocerebellar, II, Olivopontocerebellar Atrophy, OPCA with Retinal Degeneration, OPCA with Macular Degeneration and External Ophthalmoplegia, Type 6 Spinocerebellar Ataxia, Olivopontocerebellar Atrophy IVs, Spinocerebellar Ataxia-2, Spinocerebellar Ataxia-1, Spinocerebellar Ataxia-4, Syndrome, Wadia-Swami, Spinocerebellar Ataxia-6, OPCA, Schut-Haymaker Type, Atrophy II, Spinocerebellar, Menzel Type OPCA, Ataxia 5, Spinocerebellar, Spinocerebellar Ataxia-5, Spinocerebellar Ataxia-7, SCA1s, Spinocerebellar Ataxia, Dominantly-Inherited, Spinocerebellar Ataxia 5s, Olivopontocerebellar Atrophy 2s, Spinocerebellar Ataxias, Dominantly Inherited, Spinocerebellar Atrophy II, Atrophy IIs, Spinocerebellar, Olivopontocerebellar Atrophy, Holguin Type, Ataxias, Spinocerebellar, Spinocerebellar Atrophy IIs, Type 5 Spinocerebellar Ataxia, Olivopontocerebellar Atrophy 2, Ataxia, Spinocerebellar, Schut Haymaker Type OPCA, Wadia-Swami Syndrome, Ataxia 2, Spinocerebellar, Spinocerebellar Atrophies, Syndrome, Wadia Swami, Atrophy III, Olivopontocerebellar, Atrophies, Spinocerebellar, Spinocerebellar Ataxia Type 1, Ataxia 2s, Spinocerebellar, Type 4 Spinocerebellar Ataxia, Ataxia 7s, Spinocerebellar, Dominantly-Inherited Spinocerebellar Ataxia, Spinocerebellar Ataxia 7s, Spinocerebellar Ataxia, Autosomal Dominant, with Sensory Axonal Neuropathy, Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia Type 7, Spinocerebellar Ataxia Type 2, Olivopontocerebellar Atrophy Is, Spinocerebellar Ataxia Type 4, Spinocerebellar Ataxia Type 5, II, Spinocerebellar Atrophy, Spinocerebellar Ataxia 1, Spinocerebellar Ataxia 2, Atrophy II, Olivopontocerebellar