A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.

Synonyms: 0, Transcription Factor POU, POU Domain Factors, Pit-Oct-Unc Proteins, Pit Oct Unc Proteins, POU, Transcription Factor, POU Proteins