A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.

Synonyms: Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating), Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating), C-Palmitoyltransferase, Serine, Serine Palmitoyltransferase, Long Chain Base Subunit 1, Serine Palmitoyltransferase, Long Chain Base Subunit 2, Serine Palmitoyltransferase, Long Chain Base Biosynthesis Protein 2, Palmitoyltransferase 2, Serine, Long Chain Base Biosynthesis Protein 1, Serine C-Palmitoyltransferase, Serine-Palmitoyl-CoA Transferase 2, Serine Palmitoyl CoA Transferase 2, Serine Palmitoyltransferase 2, Transferase 2, Serine-Palmitoyl-CoA, Serine Palmitoyltransferase 1, Palmitoyltransferase, Serine, EC 2.3.1.50, Serine C Palmitoyltransferase, Palmitoyltransferase 1, Serine