Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.

Synonyms: 0, Protein, Wingless Type, Type Protein, Wingless, Wnt Factors, Wnt Factor, Wingless Type Proteins, Wnt Proteins, Wnt Protein, Wingless Type Protein, Protein, Wnt, Factor, Wnt